Calculateur comparatif des formules de LDL-C

État

clinical-review-pending

Version de la méthode

Friedewald 1972 and Sampson/NIH 2020 numeric LDL-C estimates in mg/dL: Friedewald LDL-C = TC - HDL-C - TG/5, applicable only when TG <400 mg/dL; Sampson/NIH LDL-C = TC/0.948 - HDL-C/0.971 - [TG/8.56 + (TG x non-HDL-C)/2140 - TG^2/16100] - 9.44, where non-HDL-C = TC - HDL-C, applicable when TG <=800 mg/dL; SI inputs are normalized with cholesterol x0.0259 and triglycerides x0.0113

Population

Adults with total cholesterol, HDL-C, and triglycerides measured contemporaneously from one fasting lipid panel, after verifying specimen identity, reported units, assay results, applicability to the Friedewald and Sampson/NIH source populations, and local analytical context.

Limites et exclusions

Martin/Hopkins or extended Martin/Hopkins estimates and any proprietary or tabular factor method. · Direct LDL-C measurement or substitution for a direct LDL-C assay. · LDL-C categories, cutoffs, targets, cardiovascular-risk estimation, diagnosis, prognosis, treatment recommendations, or management decisions. · Pediatric use; nonfasting or non-contemporaneous measurements; total cholesterol, HDL-C, and triglycerides from different panels or collections; unverified units, assay results, or source-population applicability; Friedewald use when TG >=400 mg/dL; or Sampson/NIH use when TG >800 mg/dL.

• https://pubmed.ncbi.nlm.nih.gov/4337382/
• https://pubmed.ncbi.nlm.nih.gov/32101259/

Outil importé de la bibliothèque PharmaTek de MDose. Aucune date de révision clinique indépendante n’est documentée dans cette version.

Bibliothèque source

PharmaTek · MDose

Version importée

4b66536936ed

État de publication

Révision clinique en cours