PHARMATEK · Fonction rénale

Calculateur de la clairance de l’eau libre d’électrolytes

Calculer la clairance urinaire classique brute de l’eau libre d’électrolytes à partir d’un intervalle urinaire mesuré, avec limites explicites de la composante rénale seulement.

Révision clinique en cours

La révision clinique doit être complétée.

Cet outil fait partie de la bibliothèque PharmaTek. Son calcul reste indisponible au public jusqu’à la validation de sa formule, de ses limites et de ses sources.

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Sources, population et validation

État: clinical-review-pending
Version de la méthode: Classic urinary electrolyte-free water clearance v1: C_H2O(e) = V × [1 - (U_Na + U_K) / P_Na]; measured urine flow V is normalized among mL/min, mL/hour, and L/day; sodium and potassium concentrations use explicit mmol/L or mEq/L identities that are numerically equivalent for these monovalent ions; outputs are raw, signed, and unrounded in mL/min, mL/hour, and L/day with the raw (U_Na + U_K) / P_Na ratio. This is expressly the classic renal-component equation, not the modified Edelman-derived or whole-body model
Population: People with quantitative measured urine flow plus urine sodium and urine potassium from the same collection interval and a contemporaneous plasma or serum sodium result, after verifying collection timing, specimen and analyte identities, reported units, source results, and assay context. A clinician must independently establish that the classic equation is applicable, that the interval is sufficiently representative, and that a hyperglycemia-modified model is not required. Use is limited to its renal arithmetic component with the whole-body limitation explicitly acknowledged.
Limites et exclusions: Spot urine concentrations without a measured matching urine flow; mismatched or non-contemporaneous measurements; changing urine flow or electrolyte excretion that makes the interval unrepresentative; unverified collection timing, specimen, analyte, assay, source-result, or unit identities; or inferred values or units. · Hyperglycemia or another context requiring a modified model; substitution of the modified Edelman-derived equation, whole-body electrolyte-free water clearance or balance, intake, or gastrointestinal, skin, respiratory, drain, or other nonrenal sodium, potassium, or water outputs. · Any cutoff, threshold, result category, sign-based clinical interpretation, diagnosis, prediction of future sodium direction, magnitude, or rate, fluid prescription, correction-rate plan, treatment, management, or other clinical decision.

Origine de l’outil PharmaTek

Outil importé de la bibliothèque PharmaTek de MDose. Aucune date de révision clinique indépendante n’est documentée dans cette version.

Bibliothèque source: PharmaTek · MDose
Version importée: 4b66536936ed
État de publication: Révision clinique en cours

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