PHARMATEK · Fonction rénale

Calculateur du Kt/V à compartiment unique de Daugirdas

Calculer le spKt/V brut de Daugirdas de deuxième génération à partir d’une séance vérifiée d’hémodialyse d’entretien conventionnelle.

Révision clinique en cours

La révision clinique doit être complétée.

Cet outil fait partie de la bibliothèque PharmaTek. Son calcul reste indisponible au public jusqu’à la validation de sa formule, de ses limites et de ses sources.

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Sources, population et validation

État: clinical-review-pending
Version de la méthode: Daugirdas 1993 second-generation variable-volume single-pool Kt/V arithmetic v1: R = postdialysis urea / predialysis urea; spKt/V = -ln(R - 0.008 × t) + (4 - 3.5 × R) × (UF / W), where ln is the natural logarithm, t is completed session duration in hours, UF is net ultrafiltration volume in liters, and W is measured postdialysis weight in kilograms. Pre/post urea must share one explicit BUN mg/dL or whole-urea mmol/L identity; BUN/urea normalization uses NIST nitrogen atomic weight 14.0067, with 1 mg/dL BUN = 10 / (2 × 14.0067) mmol/L whole urea. Outputs are raw and unrounded
Population: People undergoing one completed conventional maintenance-hemodialysis session for whom the Daugirdas second-generation single-pool model and source population are independently established as applicable. Predialysis and postdialysis urea results must come from that same session under one documented locally approved sampling protocol addressing collection timing, saline dilution, access technique and recirculation, and the postdialysis sampling method. Analyte identity, shared units, quantitative source results, assays, completed duration, net ultrafiltration volume, and measured postdialysis weight must be verified.
Limites et exclusions: Peritoneal dialysis; continuous, prolonged, acute, or another nonconventional renal-replacement modality; a different Kt/V equation or formal urea-kinetic model; equilibrated Kt/V (eKt/V); standardized Kt/V (stdKt/V); residual kidney clearance; or substitution of predialysis, target, estimated, or dry weight for measured postdialysis weight. · Pre/post results from different sessions; postdialysis urea greater than predialysis urea; nonpositive logarithm argument; unapproved, undocumented, or unverified sampling timing or technique; saline dilution; access or cardiopulmonary recirculation; rebound handling; mismatched BUN and whole-urea identities or units; or unverified analytes, units, assays, source results, session duration, ultrafiltration volume, or postdialysis weight. · Any adequacy target, cutoff, threshold, category, determination, or claim; dialysis prescription or dose recommendation; monitoring interval; diagnosis; prognosis; management; treatment; or other clinical decision.

Origine de l’outil PharmaTek

Outil importé de la bibliothèque PharmaTek de MDose. Aucune date de révision clinique indépendante n’est documentée dans cette version.

Bibliothèque source: PharmaTek · MDose
Version importée: 4b66536936ed
État de publication: Révision clinique en cours

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